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Neuropsychopharmacology 1996;15:45664

The clinical data demonstrate activity of ICT in the treatment of low/intermediate-1 risk MDS patients with iron overload suggesting a potency of ICT as an additional treatment option

Variants associated with greater insulin resistance or weight gain susceptibility support clinical narratives emphasizing metabolic disease rather than cosmetic weight loss

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Moreover, continued investigation into the pleiotropic effects of GLP-1 receptor agonists may reveal other therapeutic possibilities, possibly transforming the management of many metabolic and non-metabolic disorders