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The result is a growing class of compounds known as BDNF mimetic peptides, molecules that are small enough to be practical but precise enough to trigger the same downstream pathways as the native protein

The distribution of these isomers can influence physicochemical properties such as solubility, stability, and antioxidant activity, and may therefore affect bioavailability and biological function

Research shows that both naturally aged wildtype mice and fast-aging XpdTTD/TTD mice develop progressive kidney dysfunction characterized by elevated plasma urea and creatinine levels, established biomarkers of reduced glomerular filtration capacity

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