Nitrogen atoms correspond to amide and amine functionalities, while oxygen atoms are associated with carbonyl and hydroxyl groups
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However, next to the lower blood Tyr levels due to impaired conversion of Phe into Tyr, Phe has a high affinity for the large neutral amino acid (LNAA) transporter, compromising transport of all LNAAs over the blood-brain barrier (BBB), resulting in a reduction of neurotransmitter production [15, 17, 18]
H., Daley, M
Ann Pharmacother 42:16861691