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It suppresses the production of ICAM-1, IL-6, IL-8, and cyclooxygenase 2 mRNA, and prevents IL-1-induced elevations of these molecules (139)

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ROS and RNS production in physiological conditions is maintained at low levels [25, 26] and used to regulate various physiological functions, including cell signaling, homeostasis, vascular tone, and immune reactions [27]