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The combination of energy-modulating drugs is also of interest, with coenzyme Q10 combined with riboflavin or levocarnitine showing greater efficacy in alleviating migraine attacks (86, 99, 100)

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showed that NAC administration decreased homocysteine levels the greatest in patients with some preserved renal function and had minimal effects in completely anuric patients, which supports that the beneficial effects seen are due to improvement in nephron function [50]

This study offers valuable insights into the mechanisms underlying persistent VCD associated with long COVID and highlights the therapeutic potential of vitamin B12 as an epidrug to prevent or mitigate this impairment

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