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A second direction of the interrelationship between psoriasis and obesity indicates that patients with psoriasis have elevated levels of inflammatory cytokines, particularly TNF-, which can lead to metabolic abnormalities, including insulin resistance, and may consequently lead to the development of obesity (211)

J Inherit.Metab Dis 2006;29(5):631-636

This is a theoretical risk, not a demonstrated one, and it should factor into who avoids this stack (see below)