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A smaller dose does not neutralize risk in patients with conditions such as medullary thyroid carcinoma history, MEN2, pancreatitis, gastroparesis, or pregnancy

As blood sugar levels are reduced, it becomes easier to burn more body fat

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The result is a meaningful reduction in caloric intake and a significant improvement in metabolic markers

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latency to onset 2-12 weeks [2 outliers at 1 and 2 years], hepatocellular pattern of injury, often severe, 4 were fatal or led to liver transplantation)