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Athletes subject to WADA, USADA, NCAA, or other sport-governing-body testing should not use it

Since adipose tissue is responsive to endotoxins, bacterial translocation may provide a mechanism whereby the gut microbiome can modulate the adipose metabolome (for review, Kruis et al., 2014 23 ) and consequently exacerbate obesity and its related comorbidities

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It showed methylcobalamin (a B12 form) can improve neuropathic symptoms in diabetics