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Although this phenomenon is considered the primary pathway of melanocyte destruction in vitiligo, the presence of melanocyte-specific T cells is not sufficient, as they have also been found in healthy individuals, showing an anergic phenotype.19,20 Regulatory T cells The imbalance between pro- and anti-inflammatory signaling is crucial in the pathogenesis of vitiligo

Development was discontinued because the Phase IIb trial of 536 subjects over 24 weeks failed to meet its primary efficacy endpoint

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GLP-2 Actions in the Gastrointestinal Mucosal Epithelium

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