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Safety Considerations: DAC vs No DAC The safety considerations are similar because both act on the GH/IGF-1 axis

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[DOI] [PubMed] [Google Scholar] Salehpour et al

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The generation of ROS by embryo metabolism or the culture medium has been demonstrated to induce a series of deleterious effects, including protein denaturation, apoptosis, autophagy, lipid oxidation, DNA damage, and mitochondrial impairment