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433 Methylglyoxal, a reactive dicarbonyl by-product of glycolysis, induces post-translational modifications of the voltage-gated sodium channel Nav1.8, increasing the excitability of nociceptive neurons

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Deficiencies in many of the B vitamins results in negative cognitive effects (see Consequences of Select Micronutrient Deficiencies), and a number of studies have linked lower blood levels of B vitamins with some cognitive impairments (147-154)

Plant J 41:5667 Salomon M (2005) Arzneimittel in der aquatischen Umwelt

Clinical and subjective measures Depression Depressive symptoms were assessed with the clinician-rated MontgomeryAsberg Depression Rating Scale (MADRS) as the primary measure, together with the self-report Quick Inventory of Depressive SymptomatologySelf Report (QIDSSR) and the Maudsley 3-item Depression Visual Analogue Scale (M3VAS)

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