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The observation that DNA methylation can account for rather more of the variance in serum UA than genetic polymorphisms 32 indicates the strong potential of investigation into this and other epigenetic factors in relation to risk of PD and, of course, other disorders associated with UA

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A murine transmembrane tumor necrosis factor (TNF) transgene induces arthritis by cooperative p55/p75 TNF receptor signaling

This is particularly true with the utilization of glutathione

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