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Moreover, activation of the AMP-activated protein kinase (AMPK) pathway contributes to redox balance by promoting autophagy-mediated clearance of damaged mitochondria and by upregulating Nrf2 signaling (38)

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His work often draws on large-scale health data to uncover patterns and risks in medication use across populations

Doi:10.1186/s12913-025-13461-7 12

Most cases of constipation are mild to moderate and tend to improve as the body adjusts to the medication, typically within the first few weeks to months of treatment