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The foundational mechanism papers from the Washington State University lab that described how Dihexa works were retracted in April 2025 following a misconduct finding, with a third paper under an Expression of Concern since 2021

Effects, timing, and any interactions are inferred, not measured

Long-term safety

UAE Research suggests they may support nerve repair, enhance cognitive function, and protect against neurodegenerative conditions, though more studies are needed to confirm their efficacy and safety for these purposes

Hence, this phenomenon requires further investigation

Ultimately, 76 patients completed the study, but 16 were excluded from the final analysis due to missing or mishandled samples