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Stopping biologic therapy or immunosuppressants without medical guidance can trigger a flare

Tribromoanisole is produced when naturally-occurring airborne fungi and/or bacteria (usually Aspergillus sp., Penicillium sp., Actinomycetes , Botrytis cinerea , Rhizobium sp., or Streptomyces ) are presented with brominated phenolic compounds, which they then convert into bromoanisole derivatives

J Rheumatol, 1999

Biochemical and biophysical research communications, 280(1), 132138

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