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10.1172/jci139597 26 ChettouhH.MowforthO.Galeano-DalmauN.BezawadaN.Ross-InnesC.MacRaeS.et al (2018)

Appl Microbiol Biotechnol 74:676682

Discard the used needle into a Sharps container, syringes are single use only

IM B12 is usually hydroxocobalamin or cyanocobalamin

Pemetrexed Injection Dosage and Administration 2.1 Premedication and Concomitant Medications to Mitigate Toxicity Vitamin Supplementation Initiate folic acid 400 mcg to 1000 mcg orally once daily, beginning 7 days before the first dose of Pemetrexed Injection and continuing until 21 days after the last dose of Pemetrexed Injection [see Warnings and Precautions (5.1)]

The syringe measures volume (mL), the peptide vial label states mass (mg or mcg), and the patient must convert between them using the reconstitution ratio