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A recent systematic review also identified 33 registered clinical trials examining GLP-1s for substance use disorders, with growing interest in opioid and stimulant dependencies

doi: 10.1016/j.bbamcr.2011.06.005

Prescribing: Providers may be more comfortable prescribing medications for approved indications

Brain regions involved in the ability of peptides, primarily GLP-1, to normalize alcohol-mediated behavior and neurochemical changes are associated with the GLP-1R in those areas that are important for reward

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Both Wegovy and Zepbound can deliver transformative results, but the best option depends on: Your medical history Hormone balance Appetite patterns Blood sugar stability Weight-loss goals How quickly you want to see results