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Jakafi (ruxolitinib) Indication(s): Intermediate or highrisk myelofibrosis, polycythemia vera (after hydroxyurea failure), acute graftversushost disease (GVHD) and chronic GVHD in adults (and pediatric patients 12 years and older) Manufacturer(s): Incyte (in the US)/Novartis 2024 Sales: $4.73 billion Why it sold so well: Jakafi generated approximately $2.8 billion in sales in 2024, marking a solid 8% YoY increase

[Abstract]2023 Jun 6;35(6):912-927.e7

Further research into BPC-157 TB-500 combination research is ongoing

Xin D, Li T, Chu X, et al

Frequent inactivation of cysteine dioxygenase type 1 contributes to survival of breast cancer cells and resistance to anthracyclines

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