Conclusions This review of published studies indicates that evidence for the involvement of the -glutamyl cycle and trans-sulphuration pathway in autism spectrum disorders should be further explored with higher quality and lower risk bias studies to in order to ascertain the significance of these pathways with respect to clinical outcomes
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* Correspondence: Rajarsi Mandal, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
The copper component serves as an essential cofactor for lysyl oxidase and lysyl hydroxylase, enzymes critical for proper collagen cross-linking and stability
Never adjust your dose without consulting your prescriber, as both underdosing and excessive dosing carry risks