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Slowed gastric emptying can cause or worsen pre-existing gastroparesis or, rarely, contribute to severe constipation and bowel obstruction

For starters, GLP-1 agonists stimulate the pancreas to release insulin in response to elevated blood sugar levels

Sequencing and Combination Use of SGLT2is and GLP-1 RAs There was agreement that sequential or upfront combination therapy with SGLT2is and GLP-1 RAs is appropriate for individuals with ongoing kidney progression, high cardiovascular risk or suboptimal metabolic control

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The primary advantage is dose consistency

Keep the pump container tightly closed when not in use and make sure that it is out of reach of children and pets