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The abnormal expression of GPx2 was detected in different tumors, and GPx2 was up-regulated in colorectal cancer [51, 52] and down-regulated in prostate intraepithelial neoplasia [53], suggesting that GPx2 plays complex roles in tumorigenesis [23]
8 Conclusions Besides the impairment of cellular redox homeostasis in thyroid gland cells, thyroid diseases significantly contribute to systemic redox imbalance
However, it is essential to consult healthcare professionals to determine the right course of treatment based on individual health needs
This characteristic has allowed researchers to study its systemic biological effects across multiple experimental models
