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A post-hoc analysis of the TOPCAT study showed that the risk of cardiovascular events and mortality increased by 30% and 25% in individuals with HFpEF, respectively, for each standard deviation increase in body weight variability [9]

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Splitting the dose into twice-weekly injections would alter these pharmacokinetic properties, potentially reducing peak concentrations and changing the overall exposure pattern that trials demonstrated as safe and effective

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Liang, Peter C.A

This dual action makes it a powerful tool for those struggling with diabetes