Acknowledgements Work discussed in this Review was supported by a Wellcome Trust Senior Investigator Award (095531), the Knut and Alice Wallenberg Foundation, the Swedish Research Council, the Hartwell Foundation for Biomedical Research (201500731), the Juvenile Diabetes Research Foundation (CDA-2-2013-54) and the US NIH (DK110276)
Precision is not optional
Although the difference between OA and HC serum was far less pronounced than FM and HC, limited to a single parameter, and FM serum had greater levels of anti-SGC antibodies than OA serum, it is possible that some individuals with OA have low levels of anti-SGC antibodies
However, further research is required to clarify these relationships and guide evidence-based clinical practice
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Ischemiareperfusion notably increased oxidative stress, apoptosis, and inflammatory markers, as shown by higher levels of malondialdehyde, caspase-3, TNF-, and IL-6 ( p 0.05, and homogeneity of variance using Bartletts test before the ANOVA test