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clusters exceeding the 95th quantile in 3 of 4 datasets were discarded

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It was observed that GQDs were biocompatible and the biotin-linked GQDs loaded with DOX proved to have greater uptake rather than free DOX or GQDs-DOX in A549 cell line

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The release of Hb is due to the accumulation and dissolution of iron-rich erythrocytes in the brain parenchyma, which consequently leads to iron toxicity and induces the production of ROS (Wu et al., 2011), interfering with normal function of cells and resulting in neuronal death (Zecca et al., 2004)

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Furthermore, migraine poses a risk factor for headache development, and migraine-like headache being associated with lower likelihood of headache improvement and headache freedom after one year [31]

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Glucagon receptor activation increases hepatic fat oxidation and raises resting energy expenditure

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INS-1 832/3 and MIN6B1 cells were stimulated in serum-free media plus 3 mM glucose and IBMX as indicated, with results expressed relative to time-point-specific IBMX-only baseline

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