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September 5th, 2025: Research Suggests GLP-1 Medications May Raise Kidney Cancer Risk Amid Growing Litigation A new study published in JAMA Oncology suggests that GLP-1 receptor agonists such as Ozempic and Mounjaro could increase the risk of kidney cancer, despite appearing to lower the risk of certain other cancers
Additionally, Additionally, Wei et al., through their research on ovarian cancer cells, have found that HGF derived from CAFs promotes the growth of ovarian cancer cells by strengthening the c-MET/PI3K/AKT and GRP78 signaling pathways [50]
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Equivalent amounts of lysates (50 g/sample) were electrophoresed on 412% or 420% gradient gels (Invitrogen), transferred to PVDF membranes, and membranes were probed with -Actin antibody (Sigma) or CFTR antibody combo (UNC 450, UNC596 and UNC570) at 1:1000 dilution each
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