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Common GLP-1s available in Canada (as of 2025) include: *T irzepatide is dual-acting (GIP + GLP-1), which sets it apart pharmacologically but places it in the same broader category of incretin-based therapies
The body's hormones have to adjust to that, Gonsahn-Bollie says
Emax is the inter-study variability of E max
Patients with a history of alcohol use disorder should also abstain, as even small amounts may trigger relapse, and the metabolic complications of resumed heavy drinking would be particularly detrimental in the context of diabetes or obesity management
J Nutr 134:489492 Guo X, Wang WP, Ko JK, Cho CH (1999) Involvement of neutrophils and free radicals in the potentiating effects of passive cigarette smoking on inflammatory bowel disease in rats
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