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10.1016/j.jplph.2013.10.002 185 WangF.WangZ.ZhuC
[email protected] This article was submitted to Neuroplasticity and Development, a section of the journal Frontiers in Molecular Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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These interactions, particularly the protein-protein interactions between FBXO22 and NSD2, and the cooperative binding mechanism may explain the observed sensitivity to the position of the aldehyde on the benzene ring and its proximity to the NSD2 ligand (Fig
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Introducing 3D in vitro models (such as organoids and spheroids), vascularized co-culture systems, and patient-derived xenograft models can better mimic complex in vivo physiological conditions
