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In patients, the ability to synthesize GSH in the lens decreases, and patients exhibit disrupted lens redox balance, reduced GSH concentrations, impaired GPX function, elevated iron redox levels, and increased lipid peroxidation, which indicates that age-related cataracts are closely related to ferroptosis (326, 327)

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Ectopic expression of URA3 can influence the virulence phenotypes and proteome of Candida albicans but can be overcome by targeted reintegration of URA3 at the RPS10 locus

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