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As the body adapts, most patients notice: Improved stamina More consistent daily energy Reduced mental fatigue Better sleep quality This improvement reflects increased metabolic efficiency rather than increased calorie intake

Normally distributed variables were presented as mean standard deviation (SD), while skewed variables were expressed as median (25th percentile, 75th percentile)

Emphasizing glucose-dependent action, proper timing, and risk management really helps clinicians optimize GLP-1 RA therapy during fasting.

Basal insulin analogues (such as insulin glargine or insulin degludec) provide once-daily dosing with a lower risk of hypoglycaemia compared to older insulin formulations

SW: Writing original draft

PicoLab5053, LabDiet)