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During a median follow-up of 27.5 months, lobar ICH events (OR 0.10, p = 0.015), presence of cSS (OR 0.19, p = 0.028), high white matter hyperintensities Fazekas score (OR 0.41, p = 0.007) were negatively associated with favorable outcome after adjustment for age, sex and immunosuppressive treatments
This should make us rethink our approach to these remarkable medicines
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Human clinical studies have shown promising results, including a 12-year randomized controlled trial demonstrating improved cardiovascular outcomes and reduced mortality in elderly subjects with accelerated aging [4]