Five hundred and four patients with T2DM were randomized into two arms - a flexible dose of oral semaglutide based on HbA1c and gastrointestinal tolerability (3 mg for 8 weeks, followed by either continuation of 3, 7 or 14 mg) or sitagliptin 100 mg once daily
Semaglutide, a once-weekly injection that curbs your hunger, can help you lose weight, but it works effectively when you implement certain physical and diet-related changes in your lifestyle
All participants also received lifestyle interventions
Proper Storage for Your Medication Correctly storing your semaglutide is essential for maintaining its stability and effectiveness
More Recent Semaglutide Trials Recently, 2,000 people with a BMI over 30 who were not diagnosed with diabetes took part in a double-blind trial
In addition to effects on weight and blood glucose control, early laboratory studies in mice suggest that GLP-1 RAs might work through additional biological mechanisms ( 10 , 11 )