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Genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) in ethnic populations in Texas

(Biochem Pharmacol 2018) documented a reduction of -35% in white adipose tissue, -40% in adipocyte volume, -5.1% in body weight and -30% in plasma cholesterol in just 11 days in obese mice (DIO), without any change in food intake

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Although patients with CKD and ESRD display elevated homocysteine levels, the role of hyperhomocysteinemia as a cardiovascular and mortality risk factor in this population is still to be fully elucidated and deserves further investigation [8,9,10,11,12]

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