side effects of long term tirzepatide use 18 Possible (Mounjaro, Zepbound) Tirzepatide Long-Term Side Effects: Safe

Frontiers in Neuroscience , 12 (FEB)

Bernardi, P

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When restarting, you may experience gastrointestinal side effects similar to when you first started the drug, such as nausea, diarrhea, vomiting, and abdominal discomfort

Protein synthesis is associated a with high energy cost and limits nutrient availability for growth and maintenance of body mass

GLP-1 receptors in the hypothalamus and brainstem mediate appetite suppression and increased satiety , contributing to reduced food intake and weight loss