The authors concluded that treatment with a single dose of sitagliptin, in patients already treated with the GLP-1RA liraglutide, resulted in elevations in intact GLP-1 and GIP plasma concentrations after a mixed meal test, but without changes in insulin, C-peptide, glucagon and glucose concentrations
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Alpha-ketoglutarate (AKG) is a metabolite in the Krebs cycle that supports cellular energy metabolism and aids the elimination of nitrogenous waste such as ammonia
Between the pharmacological options, the GLP-1RA, originally approved for the treatment of DM2, have been demonstrated to be useful for body weight reduction in obese individuals
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Homeostasis effects of fermented Maillard reaction products by Lactobacillus gasseri 4M13 in dextran sulfate sodium-induced colitis mice