The LAR has a number of responsibilities, including: Submitting the registration application to HSA Responding to HSA queries Providing HSA with updates on the device Ensuring that the device is compliant with HSA regulations Dealing with any post-market issues The LAR is an important part of the medical device registration process in Singapore
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When they are depicted in 3D, there should be at least some attempt to base it on an x-ray crystal structure, or a computationally minimized structure, or at the very least a plausible conformation
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