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*: infected erythrocytes incubated with 5 M benzethonium present an increase in hemolysis levels, which has not been observed at 10 M
SLC7A11 encodes xCT, a cationic amino-acid transporter that is part of the cysteine- and glutamate-specific cationic antiporter, system X c
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These mutations therefore disproportionately affect individuals with ancestry from malaria endemic regions, namely Africa, the Middle East, Southeast Asia, and the Mediterranean
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