Where semaglutide activates only the GLP-1 receptor, tirzepatide adds GIP receptor agonism, which appears to potentiate the GLP-1 effects in ways that produce superior weight loss and metabolic outcomes compared to GLP-1 agonism alone
The increasing availability of interchangeable biosimilars, combined with Cost Pluss entry into the biosimilar market, is changing that calibration
Weekly subcutaneous injections (similar to insulin pens) Dosing starts low and gradually increases No sedation or downtime required Ideal for adults with: BMI 30 (obesity) or BMI 27 + weight-related conditions (e.g., diabetes, hypertension) Not recommended for pregnant women or those with certain endocrine disorders
An unlicensed medicinal product should not be supplied where an equivalent licensed medicinal product can meet the special needs of the patient
Check blood ketone levels
Despite their complete etiology being unknown, their impact on womens health and link to hereditary factors have given them the spotlight in the world of gynaecology and endocrinology
