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Conclusions Lactate metabolism is an attractive target for new cancer therapies

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Furthermore, comprehensive reviews of antioxidant therapies have emphasized the relevance of catalase and other ROS-scavenging enzymes in mitigating the molecular cascades triggered by oxidative and nitrosative stress during sepsis (Kumar et al., 2022

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doi: 10.1038/nm.3997 [DOI] [PubMed] [Google Scholar] 149

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Future research should include controlled dietary parameters, longitudinal follow-up, and microbiome-targeted interventions to better define host-microbe-drug interactions and improve long-term outcomes in the management of obesity and type 2 diabetes

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