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Topicals containing hydroquinone, alpha and beta hydroxy acids, tretinoin, mequinol, arbutin, vitamin C, soy extracts and concoctions of multiple ingredients, including newer cosmeceuticals, are now in vogue for treatment of facial melanoses especially melasma [1] and for general skin lightening, at least of the face, neck and other exposed parts

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Therefore, these injections should be administered by a healthcare professional who can monitor for adverse reactions and adjust treatment as necessary

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Researchers might monitor cell morphology, gene expression changes, or biochemical markers such as oxidative stress indicators and extracellular matrix components

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