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Pioglitazone has lower PPAR agonism compared with rosiglitazone but has more profound effects on MASH, potentially mediated by the mitochondrial target of thiazolidinediones, specifically the mitochondrial pyruvate carrier

Yoshioka J, Schreiter ER, Lee RT

Its potential to reduce inflammation offers significant benefits for individuals suffering from chronic inflammatory diseases, including arthritis, cardiovascular disease, and autoimmune conditions

These medications work by directly activating the GLP-1 receptor, amplifying the hormones effects

Soaking chia seeds in water or liquid before consuming helps them expand and maximizes their gel-forming benefit

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