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Reconstitution Steps Draw 3.0 mL bacteriostatic water with a sterile syringe

10.1371/journal.pone.0135776 104 KimD

Administration of a non-sterile drug intended to be sterile may result in serious and potentially life-threatening adverse health consequences including infections and sepsis

Markers of pyroptosis and pulmonary vascular remodeling, as well as components of the C10:2/HSP47/NLRP3 axis, were evaluated using western blotting, ELISA, and biochemical assays

Provider assessment should account for these biological differences when adjusting doses during titration

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