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There is also accumulating evidence for the use of pycnogenol as a systemic adjuvant in the treatment of melasma

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Managing Digestive Side Effects When Taking Berberine For individuals experiencing gastrointestinal side effects whilst taking berberine, several practical strategies may help minimise discomfort and improve tolerability

These data showed that Ashwagandha demonstrates antidepressant-like effects in models of adolescent depression by attenuating apoptosis, neuroinflammation, and enhancing neurotrophic factors, thereby underscoring its potential as a therapeutic agent for early intervention in adolescent depressive disorders (86)