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As regulatory requirements become more stringent and consumer expectations for product quality and transparency continue to rise, the competitive advantage favoring larger, better-capitalized manufacturers is expected to intensify, potentially resulting in further consolidation within the industry

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The fear of potential long-term complications such as neuropathy, retinopathy, and kidney disease further exacerbates this stress, which frequently results in a clinically significant apprehension regarding complications [116, 117]

Osteocalcin regulates arterial calcification via altered Wnt signaling and glucose metabolism

PMCID: PMC10734281