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However, lethargy constitutes a more profound manifestation of illness-associated symptoms, characterized by profound drowsiness, extreme lethargy, and cognitive dullness (7)

To determine CI activity (NADH-dependent OCR), MAS plus alamethicin (2.5 g ml 1 ) and cytochrome c (10 g ml 1 ) was added onto the cells followed by 5 mM pyruvate + 5 mM malate + 1 mM NADH + 10 nM recombinant perfringolysin O at port A, 2 M rotenone + 4 M antimycin A at port B, 0.5 mM TMPD + 1 mM ascorbic acid at port C and 50 mM azide at port D

The balance between these two forms of glutathione is a key indicator of oxidative stress levels in the body

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Chauhan et al 55 reported higher MDA levels, while ceruloplasmin and transferrin levels were lower in autistic children

The PINK1 protein is mostly localized in mitochondria