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During the week of June 15, 2026, FDA issued 25 warning letters to telehealth companies over alleged false or misleading promotional claims about compounded GLP-1 productsclaims the agency views as violating the Federal Food, Drug, and Cosmetic Acts (FDCA) misbranding provisions, including Sections 502(a) and 502(n)

Meta-analyses further corroborate this effect: compared with SGLT2 inhibitors or statins, GLP-1RAs are associated with more pronounced changes in EAT, with stronger beneficial effects following long-term (over 6 months) administration

RNA-sequencing data were analysed using right-tailed Fishers exact test within the Ingenuity Pathway Analysis database

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We have also provided insights into patients weight trajectories for a long period before the introduction of anti-obesity pharmacotherapy

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