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Conversely, some patients opt for evening or nighttime administration, particularly if they experience gastrointestinal side effects such as nausea
It is important to note that whilst the drug itself may be cleared within this timeframe, the pharmacological effects of Rybelsussuch as improved glycaemic control and appetite suppressionmay diminish more rapidly once treatment is discontinued
Many people lose weight consistently over months, with plateaus that can often be managed through dose adjustments or lifestyle changes
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