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The absence of drug affinity complex modification results in a shorter receptor interaction window, allowing for transient activation that aligns with pulsatile signaling models

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In: Chowdhury MEH, Kiranyaz S, editors

This reduction produces fatigue, weight gain, mood fluctuations, and inadequate post-workout recovery

Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of randomised trials[J].The Lancet Diabetes & Endocrinology,2021,9(8):653-662