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Thus, with warfarin, thrombocytopenia is the common end result of the L-NAME and/or L-arginine administration
References: Sikiric P et al., Curr Pharm Des, 2018;24(18):20022030 Kang EA et al., Dig Dis Sci, 2013;58:33103317 Seiwerth S et al., Biomedicines, 2018;6(3):75 Additional information Reviews There are no reviews yet.
Science 297 , 240243 (2002)
After systematically dissecting the molecule into fragments, they found that the C-terminus (amino acids 177 to 191) preserves the lipolytic effect without the other GH functions
Cell-culture (3T3-L1 adipocytes) 5-Amino-1MQ at 30 M strongly reduced 1-MNA levels in mouse fat cells, confirming NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)
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