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110 However, the role of the UPS is tissue specific, e.g., in muscle cells from insulin-resistant individuals, proteasome activity is increased, contributing to muscle protein degradation and atrophy

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Roughly 30 percent lost at least 20 percent of their starting weight, compared with 3.3 percent taking the placebo

To obtain a broader view of molecular changes in ovarian function that could mediate these changes, we conducted label-free quantitative proteomics analysis (Fig

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