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Reverse cholesterol transport (RCT) is a process by which macrophages counteract the accumulation of excess cholesterol (81) (Figure 3)

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Rest of APAC 8.3.5.1

Under zinc-deficient conditions, wild-type SOD1 undergoes conformational changes resembling mutant SOD1, exposing a Derlin-1-binding region that disrupts ERAD 124,125